v go device
twiist AID systempng

Summary

V-Go is a convenient credit card-size patch pump that adheres to the skin and can be worn for 24 hours. This system is designed to be used with fast-acting insulin for people with type 2 diabetes who require 20, 30, or 40 units of insulin per day. Users can administer two units of insulin with every press of a button on the device. This device is a hybrid between injections and an insulin pump to allow for discreet dosing without the need for programming or multiple injections. 

FDA-approved for people 21 years of age and older with type 2 diabetes.

The twiist AID system was cleared by the FDA for use with CGMs that have received FDA designation as integrated continuous glucose monitors (iCGMs). As the twiist AID system gets closer to commercial availability, Sequel Med Tech will publicize the list of compatible CGM

*Recently FDA approved for people with type 1 diabetes ages 6 and up.

Components

V-Go Patch : Patch

V-Go Patch : Patch

Wearable insulin patches come with reservoirs and directions for application. They can be applied on the abdomen.

twiist  : Pump

twiist : Pump

Pump can be worn with a pump clip, adhesive patch or in a pocket.

twiist  : Controller

twiist : Controller

Pump is controlled by the twiist app on an iPhone. Data from both the pump and CGM are viewable on the twiist app Home Screen.

Twiist  : Infusion Set

Twiist : Infusion Set

An infusion set contains the thin plastic tubing that delivers insulin from the pump to the body.

Device Details

Overview

Convenient, discreet, and simple use. 

This system automatically adjusts insulin delivery according to continuous glucose monitor (CGM) readings and predicted blood sugar levels. It is the first FDA-approved AID system with Apple Watch compatibility.

Affordability and Access

$$$$
Widely covered for insulin-dependent type 2. Supplies provided by DME or pharmacy. Price range; $0-$250/Month.

$$$$
No insurance coverage data. Anticipated to be provided through Pharmacy.  

Data Monitoring Options

No Options

Yes
Compatible with Tidepool - a web-based diabetes data management system. 

Data View Options

No Options

Yes
Data is stored and can be viewed directly from the twiist app on the mobile device (iPhone), and can be linked to an Apple Watch for viewing data as well.

 

Duration and Storage

24-Hours 
Patch can be worn for up to 24 hours and works in most temperatures (not for use in hot tubs, saunas, or freezing conditions). Does not require batteries or recharging.

3-day pump 10-day sensor
Sensors last 10 days, and transmitters last 90 and work at 50ºF – 108ºF. The reservoir holds 300 units and is disposable, and the pump can be used for up to 3 years.

Vision / Auditory / Dexterity

NO text to speech
NO vibration alerts
A LOT of dexterity needed

YES text to speech
YES vibration alerts
A LOT of dexterity needed

Patient Considerations

Active Lifestyle

Limited Adjustability. No way to adjust long-acting insulin for higher activity on the fly, but the device is water-resistant. 

Waterproof. The pump, when connected to the cassette, has a rating of IP28, indicating protection from continuous immersion in water. The pump can tolerate immersion to depths of up to 12 feet (3.7 m) for 1 hour.

Avoiding Highs and Lows

Limited customizability. System requires manual dose adjustment and limits the ability to adjust insulin levels throughout the day. 

Automatically adjusts insulin delivery. Increases or decreases insulin delivery to meet glucose targets. Insulin delivery settings can be aggressive or conservative.

Comfort

Free of tubing. Patches do not have tubing, but it must be worn in areas that are easy to reach for insulin dosing. 

Low-profile. Low profile with an adhesive design that prevents the pump from catching on other objects. 

Easy Insulin Dosing

Simple with few steps. 24-hour bolus range: up to 36 units per 24 hours, doses in 2-unit increments. Preset basal rate of 20, 30, or 40 units per 24 hours.

Customizable. Can bolus from phone, smartwatch, or directly from the device without needing to be attached to your phone. The device also directly measures the volume (amount) and flow (speed) of insulin delivered with every micro-dose

Easy to Use

Simple with few steps. Patch is replaced every 24-hours with insulin administered at the click of a button. 

Watch compatible. The twiist AID system is the first FDA-approved AID system that can be directly controlled from an Apple Watch.

Fewer Fingersticks

Frequent finger-sticks are required.

Factory-calibrated sensor. Fingersticks needed for backup only.

Privacy

Hideable. Bulkier patch pump, but not as noticeable as injections. Bolus button can be used discreetly through clothing.

Discreet. The pump is in two pieces - the top (algorithm and battery) and the bottom (insulin chamber and AVS technology)